Unlocking the therapeutic potential of primary tumor-draining lymph nodes
نویسندگان
چکیده
منابع مشابه
CD8+ T Lymphocyte Subsets in Bladder Tumor Draining Lymph Nodes
Background: Cytotoxic CD8+ T cells, as essential parts of the adaptive immune system, play pivotal roles in anti-tumor immune responses. It is well documented that cytokine expression profiles and activation status of these cells during anti-tumor immune responses affect the outcome of host-tumor interaction. Objective: To investigate the percentages of CD8+ lymphocytes and their subsets in...
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Histologic, histochemical. ultrastructural. and radiolabeling characteristics of the microvasculature in regional nodes draining skin allograft sites are described. From 12 to 48 hours after grafting, these nodes show increased vascular permeability and altered lymphocyte traffic pattern. The rapid rise in lymphocyte migration indices and the apparent plugging of intermediate sinuses bylynmphoc...
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ژورنال
عنوان ژورنال: Cancer Immunology, Immunotherapy
سال: 2019
ISSN: 0340-7004,1432-0851
DOI: 10.1007/s00262-019-02330-y